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A Study of Total-Variation Based Noise-Reduction Algorithms For Low-Dose Cone-Beam Computed Tomography
Sovanlal Mukherjee, Jonathan B. Farr, Weiguang Yao
Pages - 188 - 204     |    Revised - 30-09-2016     |    Published - 31-10-2016
Volume - 10   Issue - 4    |    Publication Date - October 2016  Table of Contents
Low-Dose CBCT, Nesterov's First Order Method, Split Bregman Method, Total-Variation Method.
In low-dose cone-beam computed tomography, the reconstructed image is contaminated with excessive quantum noise. In this work, we examined the performance of two popular noise-reduction algorithms-total-variation based on the split Bregman (TVSB) and total-variation based on Nesterov's method (TVN)-on noisy imaging data from a computer-simulated Shepp-Logan phantom, a physical CATPHAN phantom and head-and-neck patient. Up to 15% Gaussian noise was added to the Shepp-Logan phantom. The CATPHAN phantom was scanned by a Varian OBI system with scanning parameters 100 kVp, 4 ms, and 20 mA. Images from the head-and-neck patient were generated by the same scanner, but with a 20-ms pulse time. The 4-ms low-dose image of the head-and-neck patient was simulated by adding Poisson noise to the 20-ms image. The performance of these two algorithms was quantitatively compared by computing the peak signal-to-noise ratio (PSNR), contrast-to-noise ratio (CNR) and the total computational time. For CATPHAN, PSNR improved by 2.3 dB and 3.1 dB with respect to the low-dose noisy image for the TVSB and TVN based methods, respectively. The maximum enhancement ratio of CNR for CATPHAN was 4.6 and 4.8 for TVSB and TVN respectively. For data for head-and-neck patient, the PSNR improvement was 2.7 dB and 3.4 dB for TVSB and TVN respectively. Convergence speed for the TVSB-based method was comparatively slower than TVN method. We conclude that TVN algorithm has more desirable properties than TVSB for image denoising.
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Dr. Sovanlal Mukherjee
Department of Radiation Oncology, St. Jude Children’s Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA - United States of America
Dr. Jonathan B. Farr
Department of Radiation Oncology, St. Jude Children’s Research Hospital - United States of America
Dr. Weiguang Yao
Department of Radiation Oncology, St. Jude Children’s Research Hospital - United States of America

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